Categorie: Link

Medical device manufacturers required to post clinical trial data from trials conducted before HHS’s Final Rule in January 2017?

http://www.fdalawblog.net/2020/03/court-determines-that-decades-worth-of-missing-data-must-be-published-on-clinicaltrials-gov-but-enforcement-of-reporting-violations-hinges-on-fda-discretion/

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Mandatory MIR Form

The new EU Manufacturer Incident Report (MIR) template (updated on June 12, 2020) is mandatory for reporting of incidents under the MDD/AIMDD or IVDD, or for serious incidents under the MDR or IVDR as of January 1, 2020.

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MHRA clinical investigation links

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/860787/Guidance_for_mfrs_on_clinical_trials_January_2020.pdf With practical instructions on when a clinical investigation is required, and the note that “notification to the MHRA will not be required if the medical device to be used is CE marked for the purpose under investigation” https://www.gov.uk/guidance/notify-mhra-about-a-clinical-investigation-for-a-medical-device

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IVDR (EU-2017/746) & corrigenda

Regulation (EU) 2017/746 of April 5, 2017 1st Corrigendum (May 3, 2019) 2nd Corrigendum (December 27, 2019) EU’s IVDR (and MDR) implementing measures rolling plan

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CIOMS’ free e-learning on the International Ethical Guidelines for Health-related Research Involving Humans

The Council for International Organizations of Medical Sciences issued the course with the main aim to learn to navigate these CIOMS guidelines. The course includes example case studies and a certificate at the end. The purpose is not to replace a GCP-certificate but to assist the reader in their understanding of how to apply these […]

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IMDRF guidances on clinical evaluation

On Clinical Investigation On Clinical Evaluation On Clinical Evidence On Adverse Event reporting

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ISO 20916:2019 – IVDs – Clinical performance studies using specimens from human subjects

ISO 20916:2019

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